Any feedback?
Literature summary extracted from
- Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface (2015), J. Biol. Chem., 290, 7027-7039 .
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.38 | factor XI + H2O | Homo sapiens | - |
factor XIa + ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.38 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.38 | factor XI + H2O | - |
Homo sapiens | factor XIa + ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.38 | factor XIIa | - |
Homo sapiens |
| 3.4.21.38 | FXII | zymogen | Homo sapiens |
| 3.4.21.38 | FXIIa | - |
Homo sapiens |
| 3.4.21.38 | Hageman factor | - |
Homo sapiens |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.21.38 | physiological function | the enzyme utilizes cell membrane-bound glycosaminoglycans to interact with the cell surface of human lung fibroblasts. The enzyme stimulates human lung fibroblast migration during idiopathic pulmonary fibrosis | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
